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Inhibition of LTA4H by bestatin in human and mouse colorectal cancer
BACKGROUND: Our preclinical data showed that the leukotriene A4 hydrolase (LTA4H) pathway plays a role in colorectal cancer (CRC). High expression of LTA4H and leukotriene B4 receptor type 1 (BLT1) were also associated with CRC survival probability. Clinical samples were evaluated to determine wheth...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604047/ https://www.ncbi.nlm.nih.gov/pubmed/31085102 http://dx.doi.org/10.1016/j.ebiom.2019.05.008 |