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Ammonia sensitive SLC4A11 mitochondrial uncoupling reduces glutamine induced oxidative stress
SLC4A11 is a NH(3) sensitive membrane transporter with H(+) channel-like properties that facilitates Glutamine catabolism in Human and Mouse corneal endothelium (CE). Loss of SLC4A11 activity induces oxidative stress and cell death, resulting in Congenital Hereditary Endothelial Dystrophy (CHED) wit...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604051/ https://www.ncbi.nlm.nih.gov/pubmed/31254733 http://dx.doi.org/10.1016/j.redox.2019.101260 |