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CFTR regulates B cell activation and lymphoid follicle development

BACKGROUND: Cystic fibrosis (CF) is an inherited disorder caused by mutations in the CF transmembrane conductance regulator (CFTR) gene that promotes persistent lung infection and inflammation and progressive loss of lung function. Patients with CF have increased lung lymphoid follicles (LFs) and B...

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Detalles Bibliográficos
Autores principales: Polverino, Francesca, Lu, Bao, Quintero, Joselyn Rojas, Vargas, Sara O., Patel, Avignat S., Owen, Caroline A., Gerard, Norma P., Gerard, Craig, Cernadas, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604167/
https://www.ncbi.nlm.nih.gov/pubmed/31262295
http://dx.doi.org/10.1186/s12931-019-1103-1