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Modulation of Conformational Preferences of Heteroaromatic Ethers and Amides through Protonation and Ionization: Charge Effect

Multiple approaches reveal the strong effects of a positive charge introduced by protonation or ionization on the conformation of o‐heteroaromatic ethers and amides. The ethers and amides containing an ortho‐N heteroatom are syn‐preferring while those containing an ortho‐O or ortho‐S heteroatom are...

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Detalles Bibliográficos
Autores principales: Dai, Wenshuai, Zhang, Zhe, Du, Yikui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604235/
https://www.ncbi.nlm.nih.gov/pubmed/31304077
http://dx.doi.org/10.1002/open.201900103