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Detection of low-density Plasmodium falciparum infections using amplicon deep sequencing

BACKGROUND: Deep sequencing of targeted genomic regions is becoming a common tool for understanding the dynamics and complexity of Plasmodium infections, but its lower limit of detection is currently unknown. Here, a new amplicon analysis tool, the Parallel Amplicon Sequencing Error Correction (PASE...

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Detalles Bibliográficos
Autores principales: Early, Angela M., Daniels, Rachel F., Farrell, Timothy M., Grimsby, Jonna, Volkman, Sarah K., Wirth, Dyann F., MacInnis, Bronwyn L., Neafsey, Daniel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604269/
https://www.ncbi.nlm.nih.gov/pubmed/31262308
http://dx.doi.org/10.1186/s12936-019-2856-1