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Early-life determinants of hypoxia-inducible factor 3A gene (HIF3A) methylation: a birth cohort study

BACKGROUND: Methylation of the hypoxia-inducible factor 3α gene (HIF3A) has been linked to pregnancy exposures, infant adiposity and later BMI. Genetic variation influences HIF3A methylation levels and may modify these relationships. However, data in very early life are limited, particularly in asso...

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Detalles Bibliográficos
Autores principales: Mansell, Toby, Ponsonby, Anne-Louise, Januar, Vania, Novakovic, Boris, Collier, Fiona, Burgner, David, Vuillermin, Peter, Ryan, Joanne, Saffery, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604333/
https://www.ncbi.nlm.nih.gov/pubmed/31262346
http://dx.doi.org/10.1186/s13148-019-0687-0