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LGALS3 is connected to CD74 in a previously unknown protein network that is associated with poor survival in patients with AML

BACKGROUND: Galectin 3 (LGALS3) gene expression is associated with poor survival in acute myeloid leukemia (AML) but the prognostic impact of LGALS3 protein expression in AML is unknown. LGALS3 supports diverse survival pathways including RAS mediated cascades, protein expression and stability of an...

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Detalles Bibliográficos
Autores principales: Ruvolo, Peter P., Hu, Chenyue W., Qiu, Yihua, Ruvolo, Vivian R., Go, Robin L., Hubner, Stefan E., Coombes, Kevin R., Andreeff, Michael, Qutub, Amina A., Kornblau, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604360/
https://www.ncbi.nlm.nih.gov/pubmed/31105032
http://dx.doi.org/10.1016/j.ebiom.2019.05.025