Cargando…
LGALS3 is connected to CD74 in a previously unknown protein network that is associated with poor survival in patients with AML
BACKGROUND: Galectin 3 (LGALS3) gene expression is associated with poor survival in acute myeloid leukemia (AML) but the prognostic impact of LGALS3 protein expression in AML is unknown. LGALS3 supports diverse survival pathways including RAS mediated cascades, protein expression and stability of an...
Autores principales: | Ruvolo, Peter P., Hu, Chenyue W., Qiu, Yihua, Ruvolo, Vivian R., Go, Robin L., Hubner, Stefan E., Coombes, Kevin R., Andreeff, Michael, Qutub, Amina A., Kornblau, Steven M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604360/ https://www.ncbi.nlm.nih.gov/pubmed/31105032 http://dx.doi.org/10.1016/j.ebiom.2019.05.025 |
Ejemplares similares
-
Phosphorylation of GSK3α/β correlates with activation of AKT and is prognostic for poor overall survival in acute myeloid leukemia patients
por: Ruvolo, Peter P., et al.
Publicado: (2015) -
Low Expression Of PP2A Regulatory Subunit B55α Is Associated With T308 Phosphorylation Of AKT And Shorter Complete Remission Duration In Acute Myeloid Leukemia Patients
por: Ruvolo, Peter P., et al.
Publicado: (2011) -
Bone marrow stromal cells induce an ALDH(+) stem cell-like phenotype and enhance therapy resistance in AML through a TGF-β-p38-ALDH2 pathway
por: Yuan, Bin, et al.
Publicado: (2020) -
Progeny Clustering: A Method to Identify Biological Phenotypes
por: Hu, Chenyue W., et al.
Publicado: (2015) -
Inhibition of FAO in AML co-cultured with BM adipocytes: mechanisms of survival and chemosensitization to cytarabine
por: Tabe, Yoko, et al.
Publicado: (2018)