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In-depth characterization of congenital Zika syndrome in immunocompetent mice: Antibody-dependent enhancement and an antiviral peptide therapy

BACKGROUND: Zika virus (ZIKV) infection during pregnancy may cause major congenital defects, including microcephaly, ocular, articular and muscle abnormalities, which are collectively defined as Congenital Zika Syndrome. Here, we performed an in-depth characterization of the effects of congenital ZI...

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Detalles Bibliográficos
Autores principales: Camargos, Vidyleison N., Foureaux, Giselle, Medeiros, Daniel C., da Silveira, Vivian T., Queiroz-Junior, Celso M., Matosinhos, Ana Luisa B., Figueiredo, André F.A., Sousa, Carla D.F., Moreira, Thaiane P., Queiroz, Victória F., Dias, Ana Carolina F., Santana, Karina T.O., Passos, Ingredy, Real, Ana Luíza C.V., Silva, Ludmila C., Mourão, Flávio A.G., Wnuk, Natália T., Oliveira, Milton A.P., Macari, Soraia, Silva, Tarcília, Garlet, Gustavo P., Jackman, Joshua A., Soriani, Frederico M., Moraes, Márcio F.D., Mendes, Eduardo M.A.M., Ribeiro, Fabíola M., Costa, Guilherme M.J., Teixeira, Antônio L., Cho, Nam-Joon, Oliveira, Antônio C.P., Teixeira, Mauro M., Costa, Vivian V., Souza, Danielle G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604363/
https://www.ncbi.nlm.nih.gov/pubmed/31130472
http://dx.doi.org/10.1016/j.ebiom.2019.05.014