Cardiac ischemia–reperfusion injury under insulin-resistant conditions: SGLT1 but not SGLT2 plays a compensatory protective role in diet-induced obesity

BACKGROUND: Recent large-scale clinical trials have shown that SGLT2-inhibitors reduce cardiovascular events in diabetic patients. However, the regulation and functional role of cardiac sodium–glucose cotransporter (SGLT1 is the dominant isoform) compared with those of other glucose transporters (in...

Descripción completa

Detalles Bibliográficos
Autores principales: Yoshii, Akira, Nagoshi, Tomohisa, Kashiwagi, Yusuke, Kimura, Haruka, Tanaka, Yoshiro, Oi, Yuhei, Ito, Keiichi, Yoshino, Takuya, Tanaka, Toshikazu D., Yoshimura, Michihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604374/
https://www.ncbi.nlm.nih.gov/pubmed/31262297
http://dx.doi.org/10.1186/s12933-019-0889-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604374/
https://www.ncbi.nlm.nih.gov/pubmed/31262297
http://dx.doi.org/10.1186/s12933-019-0889-y

Ejemplares similares