Aerosol immunization by alginate coated mycobacterium (BCG/MIP) particles provide enhanced immune response and protective efficacy than aerosol of plain mycobacterium against M.tb. H37Rv infection in mice

BACKGROUND: With the aim of preparing a more effective, safe and economical vaccine for tuberculosis, inhalable live mycobacterium formulations were evaluated. METHODS: Alginate particles in the size range of 2–4 μm were prepared by encapsulating live Bacille Calmette–Guérin (BCG) and “Mycobacterium...

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Detalles Bibliográficos
Autores principales: Nagpal, Puja S., Kesarwani, Ashwani, Sahu, Parul, Upadhyay, Pramod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604382/
https://www.ncbi.nlm.nih.gov/pubmed/31262260
http://dx.doi.org/10.1186/s12879-019-4157-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604382/
https://www.ncbi.nlm.nih.gov/pubmed/31262260
http://dx.doi.org/10.1186/s12879-019-4157-2

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