Simvastatin Reduces Hepatic Oxidative Stress and Endoplasmic Reticulum Stress in Nonalcoholic Steatohepatitis Experimental Model

OBJECTIVE: In this study, we evaluated the efficacy of simvastatin in the treatment of nonalcoholic steatohepatitis induced by methionine and choline-deficient diet in mice and its possible effect on factors involved in the pathogenesis of the disease including oxidative stress and endoplasmic retic...

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Detalles Bibliográficos
Autores principales: Rodrigues, Graziella, Moreira, Andrea Janz, Bona, Silvia, Schemitt, Elizângela, Marroni, Cláudio Augusto, Di Naso, Fábio Cangeri, Dias, Alexandre Simões, Pires, Thienne Rocha, Picada, Jaqueline Nascimento, Marroni, Norma Possa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604429/
https://www.ncbi.nlm.nih.gov/pubmed/31316716
http://dx.doi.org/10.1155/2019/3201873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604429/
https://www.ncbi.nlm.nih.gov/pubmed/31316716
http://dx.doi.org/10.1155/2019/3201873

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