Microglia – mediated immunity partly contributes to the genetic association between Alzheimer’s disease and hippocampal volume

Genome-wide association studies (GWAS) suggest that Alzheimer’s disease (AD) is partly explained by a burden of risk alleles (single nucleotide polymorphisms; SNPs) with relatively small effects. However, the mechanisms by which these loci cumulatively confer susceptibility remain largely unknown. A...

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Detalles Bibliográficos
Autores principales: Lancaster, T.M., Hill, M.J., Sims, R., Williams, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605284/
https://www.ncbi.nlm.nih.gov/pubmed/30776473
http://dx.doi.org/10.1016/j.bbi.2019.02.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605284/
https://www.ncbi.nlm.nih.gov/pubmed/30776473
http://dx.doi.org/10.1016/j.bbi.2019.02.011

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