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Generation and characterization of a monoclonal antibody against MERS-CoV targeting the spike protein using a synthetic peptide epitope-CpG-DNA-liposome complex

Middle East respiratory syndrome coronavirus (MERS-CoV) uses the spike (S) glycoprotein to recognize and enter target cells. In this study, we selected two epitope peptide sequences within the receptor binding domain (RBD) of the MERS-CoV S protein. We used a complex consisting of the epitope peptid...

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Detalles Bibliográficos
Autores principales: Park, Byoung Kwon, Maharjan, Sony, Lee, Su In, Kim, Jinsoo, Bae, Joon-Yong, Park, Man-Seong, Kwon, Hyung-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605520/
https://www.ncbi.nlm.nih.gov/pubmed/30355437
http://dx.doi.org/10.5483/BMBRep.2019.52.6.185