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Botulinum toxin type A prevents the phenotypic transformation of fibroblasts induced by TGF-β1 via the PTEN/PI3K/Akt signaling pathway

Hypertrophic scar (HS) is a common type of dermatosis. Botulinum toxin type A (BTXA) can exert an anti-HS effect; however, the regulatory mechanisms underlying this effect remain unclear. Thus, the aim of this study was to examine the effects of BTXA on phosphatase and tensin homolog deleted on chro...

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Detalles Bibliográficos
Autores principales: Zhang, Xue, Lan, Dong, Ning, Shuhua, Jia, Hongxia, Yu, Sisi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605626/
https://www.ncbi.nlm.nih.gov/pubmed/31173164
http://dx.doi.org/10.3892/ijmm.2019.4226