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Tetramethylpyrazine protects retinal ganglion cells against H(2)O(2)-induced damage via the microRNA-182/mitochondrial pathway

Glaucoma is the leading cause of irreversible blindness worldwide; the apoptosis of the retinal ganglion cells (RGCs) is a hallmark of glaucoma. Tetramethylpyrazine (TMP) is the main active component of Ligusticum wallichii Franchat, and has been demonstrated to improve a variety of injuries through...

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Detalles Bibliográficos
Autores principales: Li, Xinmin, Wang, Qiuli, Ren, Yanfan, Wang, Xiaomin, Cheng, Huaxu, Yang, Hua, Wang, Baojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605642/
https://www.ncbi.nlm.nih.gov/pubmed/31173163
http://dx.doi.org/10.3892/ijmm.2019.4214