Cargando…

Tetramethylpyrazine protects retinal ganglion cells against H(2)O(2)-induced damage via the microRNA-182/mitochondrial pathway

Glaucoma is the leading cause of irreversible blindness worldwide; the apoptosis of the retinal ganglion cells (RGCs) is a hallmark of glaucoma. Tetramethylpyrazine (TMP) is the main active component of Ligusticum wallichii Franchat, and has been demonstrated to improve a variety of injuries through...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Xinmin, Wang, Qiuli, Ren, Yanfan, Wang, Xiaomin, Cheng, Huaxu, Yang, Hua, Wang, Baojun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605642/ https://www.ncbi.nlm.nih.gov/pubmed/31173163 http://dx.doi.org/10.3892/ijmm.2019.4214

Ejemplares similares

Targeted deletion of miR-182, an abundant retinal microRNA
por: Jin, Zi-Bing, et al.
Publicado: (2009)

Bone protection by inhibition of microRNA-182
por: Inoue, Kazuki, et al.
Publicado: (2018)

MicroRNA-183/96/182 cluster in immunity and autoimmunity
por: Wang, Zhuang, et al.
Publicado: (2023)

Down-regulation of microRNA-182 and microRNA-183 predicts progression of osteosarcoma
por: Golbakhsh, Mohammad Reza, et al.
Publicado: (2016)

Prognostic Value of MicroRNA-182 in Cancers: A Meta-Analysis
por: Wang, Fei, et al.
Publicado: (2015)

MicroRNA-182 Regulates Neurite Outgrowth Involving the PTEN/AKT Pathway
por: Wang, Wu M., et al.
Publicado: (2017)

MicroRNA-182 downregulates metastasis suppressor 1 and contributes to metastasis of hepatocellular carcinoma
por: Wang, Jian, et al.
Publicado: (2012)

Role of MicroRNA-223 and MicroRNA-182 as Novel Biomarkers in Early Detection of Colorectal Cancer
por: Mahmoud, Hala A, et al.
Publicado: (2022)

Role of MicroRNA-182 in Posterior Uveal Melanoma: Regulation of Tumor Development through MITF, BCL2 and Cyclin D2
por: Yan, Dongsheng, et al.
Publicado: (2012)

Tetramethylpyrazine Ameliorates High Glucose-Induced Endothelial Dysfunction by Increasing Mitochondrial Biogenesis
por: Xu, Qiong, et al.
Publicado: (2014)

Expression and regulatory effects of microRNA-182 in osteosarcoma cells: A pilot study
por: BIAN, DONG-LIN, et al.
Publicado: (2016)

MicroRNA-182 Suppresses HGF/SF-Induced Increases in Retinal Pigment Epithelial Cell Proliferation and Migration through Targeting c-Met
por: Wang, Lihua, et al.
Publicado: (2016)

Hypoxia-ischemia and retinal ganglion cell damage
por: Kaur, Charanjit, et al.
Publicado: (2008)

microRNA-182 targets special AT-rich sequence-binding protein 2 to promote colorectal cancer proliferation and metastasis
por: Yang, Min-Hui, et al.
Publicado: (2014)

MicroRNA-182 promotes proliferation and metastasis by targeting FOXF2 in triple-negative breast cancer
por: Zhang, Xingzeng, et al.
Publicado: (2017)

Protective Effects and Mechanisms of MicroRNA-182 on Oxidative Stress in RHiN
por: Li, Lihua, et al.
Publicado: (2019)

The emerging role of MicroRNA-182 in tumorigenesis; a promising therapeutic target
por: Sameti, Pouriya, et al.
Publicado: (2023)

Prognostic role of microRNA 182 and microRNA 18a in locally advanced triple negative breast cancer
por: Bajaj, Rajat, et al.
Publicado: (2020)

MicroRNA-182-5p Attenuates Asthmatic Airway Inflammation by Targeting NOX4
por: Wang, Zhiguang, et al.
Publicado: (2022)

Downregulation of microRNA-100 protects apoptosis and promotes neuronal growth in retinal ganglion cells
por: Kong, Ning, et al.
Publicado: (2014)

MicroRNA-182 Promotes Cell Migration by Targeting Programmed Cell Death 4 in Hepatocellular Carcinoma Cells
por: Hu, Junwei, et al.
Publicado: (2020)

Tetramethylpyrazine Attenuates the Endotheliotoxicity and the Mitochondrial Dysfunction by Doxorubicin via 14-3-3γ/Bcl-2
por: Yang, Bin, et al.
Publicado: (2019)

MicroRNA-93/STAT3 signalling pathway mediates retinal microglial activation and protects retinal ganglion cells in an acute ocular hypertension model
por: Wang, Yayi, et al.
Publicado: (2021)

High expression of microRNA-183/182/96 cluster as a prognostic biomarker for breast cancer
por: Song, Cailu, et al.
Publicado: (2016)

Structural insights into the human GW182-PABC interaction in microRNA-mediated deadenylation
por: Jinek, Martin, et al.
Publicado: (2010)

Sp1-mediated microRNA-182 expression regulates lung cancer progression
por: Yang, Wen-Bin, et al.
Publicado: (2014)

Potential Diagnostic and Prognostic Value of Plasma Circulating MicroRNA-182 in Human Glioma
por: Xiao, Yilei, et al.
Publicado: (2016)

Inhibition of MicroRNA-182/183 Cluster Ameliorates Schizophrenia by Activating the Axon Guidance Pathway and Upregulating DCC
por: Wang, Zhichao, et al.
Publicado: (2022)

Taurine deficiency damages retinal neurones: cone photoreceptors and retinal ganglion cells
por: Gaucher, David, et al.
Publicado: (2012)

MicroRNA-30b regulates the polarity of retinal ganglion cells by inhibiting semaphorin-3A
por: Chan-Juan, Huang, et al.
Publicado: (2019)

Brimonidine is Neuroprotective in Animal Paradigm of Retinal Ganglion Cell Damage
por: Conti, Federica, et al.
Publicado: (2021)

Tetramethylpyrazine Protects Retinal Capillary Endothelial Cells (TR-iBRB2) against IL-1β-Induced Nitrative/Oxidative Stress
por: Zhu, Xue, et al.
Publicado: (2015)

MicroRNA-19a-PTEN Axis Is Involved in the Developmental Decline of Axon Regenerative Capacity in Retinal Ganglion Cells
por: Mak, Heather K., et al.
Publicado: (2020)

Comparative MicroRNA Expression Profiles of Cynomolgus Monkeys, Rat, and Human Reveal that miR-182 Is Involved in T2D Pathogenic Processes
por: Zhou, Jinghui, et al.
Publicado: (2014)

microRNA-182 Negatively Influences the Neuroprotective Effect of Apelin Against Neuronal Injury in Epilepsy
por: Dong, Han, et al.
Publicado: (2020)

MicroRNA-182 promotes epithelial-mesenchymal transition by targeting FOXN3 in gallbladder cancer
por: Zhang, Jianhong, et al.
Publicado: (2021)

Tetramethylpyrazine inhibits CTGF and Smad2/3 expression and proliferation of hepatic stellate cells
por: Li, Jun, et al.
Publicado: (2015)

Protective Effect of Tetramethylpyrazine on Myocardial Ischemia-Reperfusion Injury
por: Qian, Weidong, et al.
Publicado: (2014)

MicroRNA-182 drives colonization and macroscopic metastasis via targeting its suppressor SNAI1 in breast cancer
por: Zhan, Yun, et al.
Publicado: (2016)

Tetramethylpyrazine Retards the Progression and Fibrogenesis of Endometriosis
por: Huang, Shenghui, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ng62u04tnsg60m27f5eeug6r5a