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Vaccinia viral A26 protein is a fusion suppressor of mature virus and triggers membrane fusion through conformational change at low pH

Vaccinia mature virus requires A26 envelope protein to mediate acid-dependent endocytosis into HeLa cells in which we hypothesized that A26 protein functions as an acid-sensitive membrane fusion suppressor. Here, we provide evidence showing that N-terminal domain (aa1-75) of A26 protein is an acid-s...

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Detalles Bibliográficos
Autores principales: Chang, Hung-Wei, Yang, Cheng-Han, Luo, Yu-Chun, Su, Bo-Gang, Cheng, Huei-Yin, Tung, Shu-Yun, Carillo, Kathleen Joyce D., Liao, Yi-Ting, Tzou, Der-Lii M., Wang, Hao-Ching, Chang, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605681/
https://www.ncbi.nlm.nih.gov/pubmed/31220181
http://dx.doi.org/10.1371/journal.ppat.1007826