CtIP is essential for early B cell proliferation and development in mice

B cell development requires efficient proliferation and successful assembly and modifications of the immunoglobulin gene products. CtIP is an essential gene implicated in end resection and DNA repair. Here, we show that CtIP is essential for early B cell development but dispensable in naive B cells....

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Xiangyu, Wang, Xiaobin S., Lee, Brian J., Wu-Baer, Foon K., Lin, Xiaohui, Shao, Zhengping, Estes, Verna M., Gautier, Jean, Baer, Richard, Zha, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605744/
https://www.ncbi.nlm.nih.gov/pubmed/31097467
http://dx.doi.org/10.1084/jem.20181139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605744/
https://www.ncbi.nlm.nih.gov/pubmed/31097467
http://dx.doi.org/10.1084/jem.20181139

Ejemplares similares