The COMMD3/8 complex determines GRK6 specificity for chemoattractant receptors

Lymphocyte migration is mediated by G protein–coupled receptors (GPCRs) that respond to chemoattractive molecules. After their activation, GPCRs are phosphorylated by different GPCR kinases (GRKs), which produces distinct functional outcomes through β-arrestins. However, the molecular machinery that...

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Detalles Bibliográficos
Autores principales: Nakai, Akiko, Fujimoto, Jun, Miyata, Haruhiko, Stumm, Ralf, Narazaki, Masashi, Schulz, Stefan, Baba, Yoshihiro, Kumanogoh, Atsushi, Suzuki, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605747/
https://www.ncbi.nlm.nih.gov/pubmed/31088898
http://dx.doi.org/10.1084/jem.20181494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605747/
https://www.ncbi.nlm.nih.gov/pubmed/31088898
http://dx.doi.org/10.1084/jem.20181494

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