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Sphingosine-1-phosphate receptor 2 restrains egress of γδ T cells from the skin

Maintenance of a population of IL-17–committed γδ T cells in the dermis is important in promoting tissue immunity. However, the signals facilitating γδ T cell retention within the dermis remain poorly understood. Here, we find that sphingosine-1-phosphate receptor 2 (S1PR2) acts in a cell-intrinsic...

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Detalles Bibliográficos
Autores principales: Laidlaw, Brian J., Gray, Elizabeth E., Zhang, Yang, Ramírez-Valle, Francisco, Cyster, Jason G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605748/
https://www.ncbi.nlm.nih.gov/pubmed/31160320
http://dx.doi.org/10.1084/jem.20190114