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Sphingosine-1-phosphate receptor 2 restrains egress of γδ T cells from the skin
Maintenance of a population of IL-17–committed γδ T cells in the dermis is important in promoting tissue immunity. However, the signals facilitating γδ T cell retention within the dermis remain poorly understood. Here, we find that sphingosine-1-phosphate receptor 2 (S1PR2) acts in a cell-intrinsic...
Autores principales: | Laidlaw, Brian J., Gray, Elizabeth E., Zhang, Yang, Ramírez-Valle, Francisco, Cyster, Jason G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605748/ https://www.ncbi.nlm.nih.gov/pubmed/31160320 http://dx.doi.org/10.1084/jem.20190114 |
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