c-MYC regulates mRNA translation efficiency and start-site selection in lymphoma

The oncogenic c-MYC (MYC) transcription factor has broad effects on gene expression and cell behavior. We show that MYC alters the efficiency and quality of mRNA translation into functional proteins. Specifically, MYC drives the translation of most protein components of the electron transport chain...

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Detalles Bibliográficos
Autores principales: Singh, Kamini, Lin, Jianan, Zhong, Yi, Burčul, Antonija, Mohan, Prathibha, Jiang, Man, Sun, Liping, Yong-Gonzalez, Vladimir, Viale, Agnes, Cross, Justin R., Hendrickson, Ronald C., Rätsch, Gunnar, Ouyang, Zhengqing, Wendel, Hans-Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605752/
https://www.ncbi.nlm.nih.gov/pubmed/31142587
http://dx.doi.org/10.1084/jem.20181726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605752/
https://www.ncbi.nlm.nih.gov/pubmed/31142587
http://dx.doi.org/10.1084/jem.20181726

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