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The E3 ligase VHL promotes follicular helper T cell differentiation via glycolytic-epigenetic control
Follicular helper T (Tfh) cells are essential for germinal center formation and effective humoral immunity, which undergo different stages of development to become fully polarized. However, the detailed mechanisms of their regulation remain unsolved. Here we found that the E3 ubiquitin ligase VHL wa...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605754/ https://www.ncbi.nlm.nih.gov/pubmed/31123085 http://dx.doi.org/10.1084/jem.20190337 |