The E3 ligase VHL promotes follicular helper T cell differentiation via glycolytic-epigenetic control

Follicular helper T (Tfh) cells are essential for germinal center formation and effective humoral immunity, which undergo different stages of development to become fully polarized. However, the detailed mechanisms of their regulation remain unsolved. Here we found that the E3 ubiquitin ligase VHL wa...

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Detalles Bibliográficos
Autores principales: Zhu, Yangyang, Zhao, Yanxia, Zou, Le, Zhang, Danfeng, Aki, Daisuke, Liu, Yun-Cai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605754/
https://www.ncbi.nlm.nih.gov/pubmed/31123085
http://dx.doi.org/10.1084/jem.20190337

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