TCF-1 limits the formation of Tc17 cells via repression of the MAF–RORγt axis

Interleukin (IL)-17–producing CD8(+) T (Tc17) cells have emerged as key players in host-microbiota interactions, infection, and cancer. The factors that drive their development, in contrast to interferon (IFN)-γ–producing effector CD8(+) T cells, are not clear. Here we demonstrate that the transcrip...

Descripción completa

Detalles Bibliográficos
Autores principales: Mielke, Lisa A., Liao, Yang, Clemens, Ella Bridie, Firth, Matthew A., Duckworth, Brigette, Huang, Qiutong, Almeida, Francisca F., Chopin, Michael, Koay, Hui-Fern, Bell, Carolyn A., Hediyeh-Zadeh, Soroor, Park, Simone L., Raghu, Dinesh, Choi, Jarny, Putoczki, Tracy L., Hodgkin, Philip D., Franks, Ashley E., Mackay, Laura K., Godfrey, Dale I., Davis, Melissa J., Xue, Hai-Hui, Bryant, Vanessa L., Kedzierska, Katherine, Shi, Wei, Belz, Gabrielle T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605755/
https://www.ncbi.nlm.nih.gov/pubmed/31142588
http://dx.doi.org/10.1084/jem.20181778

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605755/
https://www.ncbi.nlm.nih.gov/pubmed/31142588
http://dx.doi.org/10.1084/jem.20181778

Ejemplares similares