Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3

The RNase Regnase-1 is a master RNA regulator in macrophages and T cells that degrades cellular and viral RNA upon NF-κB signaling. The roles of its family members, however, remain largely unknown. Here, we analyzed Regnase-3–deficient mice, which develop hypertrophic lymph nodes. We used various mi...

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Detalles Bibliográficos
Autores principales: von Gamm, Matthias, Schaub, Annalisa, Jones, Alisha N., Wolf, Christine, Behrens, Gesine, Lichti, Johannes, Essig, Katharina, Macht, Anna, Pircher, Joachim, Ehrlich, Andreas, Davari, Kathrin, Chauhan, Dhruv, Busch, Benjamin, Wurst, Wolfgang, Feederle, Regina, Feuchtinger, Annette, Tschöp, Matthias H., Friedel, Caroline C., Hauck, Stefanie M., Sattler, Michael, Geerlof, Arie, Hornung, Veit, Heissmeyer, Vigo, Schulz, Christian, Heikenwalder, Mathias, Glasmacher, Elke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605757/
https://www.ncbi.nlm.nih.gov/pubmed/31126966
http://dx.doi.org/10.1084/jem.20181762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605757/
https://www.ncbi.nlm.nih.gov/pubmed/31126966
http://dx.doi.org/10.1084/jem.20181762

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