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Defects in the origin licensing checkpoint stresses cells exiting G0
The full licensing of replication origins in late G1 is normally enforced by the licensing checkpoint. In this issue, Matson et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201902143) show that this checkpoint is inoperative in cells exiting from G0, resulting in incomplete origin licensing...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Rockefeller University Press
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605787/ https://www.ncbi.nlm.nih.gov/pubmed/31266845 http://dx.doi.org/10.1083/jcb.201905181 |