The exocyst controls lysosome secretion and antigen extraction at the immune synapse of B cells

B lymphocytes capture antigens from the surface of presenting cells by forming an immune synapse. Local secretion of lysosomes, which are guided to the synaptic membrane by centrosome repositioning, can facilitate the extraction of immobilized antigens. However, the molecular basis underlying their...

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Detalles Bibliográficos
Autores principales: Sáez, Juan José, Diaz, Jheimmy, Ibañez, Jorge, Bozo, Juan Pablo, Cabrera Reyes, Fernanda, Alamo, Martina, Gobert, François-Xavier, Obino, Dorian, Bono, María Rosa, Lennon-Duménil, Ana-María, Yeaman, Charles, Yuseff, María-Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605794/
https://www.ncbi.nlm.nih.gov/pubmed/31197029
http://dx.doi.org/10.1083/jcb.201811131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605794/
https://www.ncbi.nlm.nih.gov/pubmed/31197029
http://dx.doi.org/10.1083/jcb.201811131

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