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A specific isoform of Pyd/ZO-1 mediates junctional remodeling and formation of slit diaphragms
The podocyte slit diaphragm (SD), responsible for blood filtration in vertebrates, is a major target of injury in chronic kidney disease. The damage includes severe morphological changes with destabilization of SDs and their replacement by junctional complexes between abnormally broadened foot proce...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605796/ https://www.ncbi.nlm.nih.gov/pubmed/31171632 http://dx.doi.org/10.1083/jcb.201810171 |