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The stoichiometry of the outer kinetochore is modulated by microtubule-proximal regulatory factors

The kinetochore is a large molecular machine that attaches chromosomes to microtubules and facilitates chromosome segregation. The kinetochore includes submodules that associate with the centromeric DNA and submodules that attach to microtubules. Additional copies of several submodules of the kineto...

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Detalles Bibliográficos
Autores principales: Dhatchinamoorthy, Karthik, Unruh, Jay R., Lange, Jeffrey J., Levy, Michaella, Slaughter, Brian D., Gerton, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605801/
https://www.ncbi.nlm.nih.gov/pubmed/31118239
http://dx.doi.org/10.1083/jcb.201810070