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Augmin accumulation on long-lived microtubules drives amplification and kinetochore-directed growth

Dividing cells reorganize their microtubule cytoskeleton into a bipolar spindle, which moves one set of sister chromatids to each nascent daughter cell. Early spindle assembly models postulated that spindle pole–derived microtubules search the cytoplasmic space until they randomly encounter a kineto...

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Detalles Bibliográficos
Autores principales: David, Ana F., Roudot, Philippe, Legant, Wesley R., Betzig, Eric, Danuser, Gaudenz, Gerlich, Daniel W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605806/
https://www.ncbi.nlm.nih.gov/pubmed/31113824
http://dx.doi.org/10.1083/jcb.201805044