SFI1 promotes centriole duplication by recruiting USP9X to stabilize the microcephaly protein STIL

In mammals, centrioles participate in brain development, and human mutations affecting centriole duplication cause microcephaly. Here, we identify a role for the mammalian homologue of yeast SFI1, involved in the duplication of the yeast spindle pole body, as a critical regulator of centriole duplic...

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Detalles Bibliográficos
Autores principales: Kodani, Andrew, Moyer, Tyler, Chen, Allen, Holland, Andrew, Walsh, Christopher A., Reiter, Jeremy F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605807/
https://www.ncbi.nlm.nih.gov/pubmed/31197030
http://dx.doi.org/10.1083/jcb.201803041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605807/
https://www.ncbi.nlm.nih.gov/pubmed/31197030
http://dx.doi.org/10.1083/jcb.201803041

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