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The enemy of my enemy: PTEN and PLCXD collude to fight endosomal PtdIns(4,5)P(2)
Loss of the phosphoinositide 5-phosphatase OCRL causes accumulation of PtdIns(4,5)P(2) on membranes and, ultimately, Lowe syndrome. In this issue, Mondin et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201805155) discover that a surprising partnership between PTEN and the phospholipase PLCXD...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605809/ https://www.ncbi.nlm.nih.gov/pubmed/31189610 http://dx.doi.org/10.1083/jcb.201906022 |