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The enemy of my enemy: PTEN and PLCXD collude to fight endosomal PtdIns(4,5)P(2)

Loss of the phosphoinositide 5-phosphatase OCRL causes accumulation of PtdIns(4,5)P(2) on membranes and, ultimately, Lowe syndrome. In this issue, Mondin et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201805155) discover that a surprising partnership between PTEN and the phospholipase PLCXD...

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Detalles Bibliográficos
Autores principales: Del Signore, Steven J., Rodal, Avital A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605809/
https://www.ncbi.nlm.nih.gov/pubmed/31189610
http://dx.doi.org/10.1083/jcb.201906022