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Discovery and mechanisms of host defense to oncogenesis: targeting the β-defensin-1 peptide as a natural tumor inhibitor

Human beta-defensin-1 (hBD-1) is one of a number of small cationic host-defense peptides. Besides its well-known broad-spectrum antimicrobial function, hBD-1 has recently been identified as a chromosome 8p tumor-suppressor gene. The role of hBD-1 in modulating the host immune response to oncogenesis...

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Detalles Bibliográficos
Autores principales: Sun, Carrie Q., Arnold, Rebecca S., Hsieh, Chia-Ling, Dorin, Julia R., Lian, Fei, Li, Zhenghong, Petros, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605992/
https://www.ncbi.nlm.nih.gov/pubmed/30900935
http://dx.doi.org/10.1080/15384047.2018.1564564