DDGun: an untrained method for the prediction of protein stability changes upon single and multiple point variations

BACKGROUND: Predicting the effect of single point variations on protein stability constitutes a crucial step toward understanding the relationship between protein structure and function. To this end, several methods have been developed to predict changes in the Gibbs free energy of unfolding (∆∆G) b...

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Detalles Bibliográficos
Autores principales: Montanucci, Ludovica, Capriotti, Emidio, Frank, Yotam, Ben-Tal, Nir, Fariselli, Piero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606456/
https://www.ncbi.nlm.nih.gov/pubmed/31266447
http://dx.doi.org/10.1186/s12859-019-2923-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606456/
https://www.ncbi.nlm.nih.gov/pubmed/31266447
http://dx.doi.org/10.1186/s12859-019-2923-1

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