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DDGun: an untrained method for the prediction of protein stability changes upon single and multiple point variations
BACKGROUND: Predicting the effect of single point variations on protein stability constitutes a crucial step toward understanding the relationship between protein structure and function. To this end, several methods have been developed to predict changes in the Gibbs free energy of unfolding (∆∆G) b...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606456/ https://www.ncbi.nlm.nih.gov/pubmed/31266447 http://dx.doi.org/10.1186/s12859-019-2923-1 |