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Pancreatic alpha-cell mass in the early-onset and advanced stage of a mouse model of experimental autoimmune diabetes

Most studies in type 1 diabetes (T1D) have focused on the loss of the pancreatic beta-cell population. However, despite the involvement of the alpha-cell in the aetiology and complications of T1D, little is known about the regulation of the pancreatic alpha-cell mass in this disease. The need for a...

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Detalles Bibliográficos
Autores principales: Bru-Tari, Eva, Cobo-Vuilleumier, Nadia, Alonso-Magdalena, Paloma, Dos Santos, Reinaldo S., Marroqui, Laura, Nadal, Angel, Gauthier, Benoit R., Quesada, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606577/
https://www.ncbi.nlm.nih.gov/pubmed/31266981
http://dx.doi.org/10.1038/s41598-019-45853-1