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A molecular switch from STAT2-IRF9 to ISGF3 underlies interferon-induced gene transcription
Cells maintain the balance between homeostasis and inflammation by adapting and integrating the activity of intracellular signaling cascades, including the JAK-STAT pathway. Our understanding of how a tailored switch from homeostasis to a strong receptor-dependent response is coordinated remains lim...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606597/ https://www.ncbi.nlm.nih.gov/pubmed/31266943 http://dx.doi.org/10.1038/s41467-019-10970-y |