A subset of topologically associating domains fold into mesoscale core-periphery networks

Mammalian genomes are folded into a hierarchy of compartments, topologically associating domains (TADs), subTADs, and long-range looping interactions. The higher-order folding patterns of chromatin contacts within TADs and how they localize to disease-associated single nucleotide variants (daSNVs) r...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Harvey, Chen, Sunnia T., Titus, Katelyn R., Emerson, Daniel J., Bassett, Danielle S., Phillips-Cremins, Jennifer E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606598/
https://www.ncbi.nlm.nih.gov/pubmed/31266973
http://dx.doi.org/10.1038/s41598-019-45457-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606598/
https://www.ncbi.nlm.nih.gov/pubmed/31266973
http://dx.doi.org/10.1038/s41598-019-45457-9

Ejemplares similares