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A subset of topologically associating domains fold into mesoscale core-periphery networks
Mammalian genomes are folded into a hierarchy of compartments, topologically associating domains (TADs), subTADs, and long-range looping interactions. The higher-order folding patterns of chromatin contacts within TADs and how they localize to disease-associated single nucleotide variants (daSNVs) r...
Autores principales: | Huang, Harvey, Chen, Sunnia T., Titus, Katelyn R., Emerson, Daniel J., Bassett, Danielle S., Phillips-Cremins, Jennifer E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606598/ https://www.ncbi.nlm.nih.gov/pubmed/31266973 http://dx.doi.org/10.1038/s41598-019-45457-9 |
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