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The Epstein-Barr Virus Oncoprotein, LMP1, Regulates the Function of SENP2, a SUMO-protease

Epstein-Barr virus (EBV) latent membrane protein-1 (LMP1) activates numerous signal transduction pathways using its C-terminal activating regions. We reported that LMP1 increased global levels of sumoylated proteins, which aided the oncogenic nature of LMP1. Because increased protein sumoylation is...

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Detalles Bibliográficos
Autores principales: Selby, Thomas L., Biel, Natalie, Varn, Matthew, Patel, Sheetal, Patel, Akash, Hilding, Leslie, Ray, Ashley, Ross, Tabithia, Cramblet, Wyatt T., Moss, C. Randall, Lowrey, Angela J., Bentz, Gretchen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606635/
https://www.ncbi.nlm.nih.gov/pubmed/31266997
http://dx.doi.org/10.1038/s41598-019-45825-5