Evaluation of microneedles-assisted in situ depot forming poloxamer gels for sustained transdermal drug delivery

In this study, for the first time, we have reported a sustained transdermal drug delivery from thermoresponsive poloxamer depots formed within the skin micropores following microneedle (MN) application. Firstly, we have investigated the sol–gel phase transition characteristics of poloxamers (PF®127,...

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Detalles Bibliográficos
Autores principales: Khan, Samiullah, Minhas, Muhammad Usman, Tekko, Ismaiel A., Donnelly, Ryan F., Thakur, Raghu Raj Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606675/
https://www.ncbi.nlm.nih.gov/pubmed/30675693
http://dx.doi.org/10.1007/s13346-019-00617-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606675/
https://www.ncbi.nlm.nih.gov/pubmed/30675693
http://dx.doi.org/10.1007/s13346-019-00617-2

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