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Evaluation of microneedles-assisted in situ depot forming poloxamer gels for sustained transdermal drug delivery

In this study, for the first time, we have reported a sustained transdermal drug delivery from thermoresponsive poloxamer depots formed within the skin micropores following microneedle (MN) application. Firstly, we have investigated the sol–gel phase transition characteristics of poloxamers (PF®127,...

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Detalles Bibliográficos
Autores principales:	Khan, Samiullah, Minhas, Muhammad Usman, Tekko, Ismaiel A., Donnelly, Ryan F., Thakur, Raghu Raj Singh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606675/ https://www.ncbi.nlm.nih.gov/pubmed/30675693 http://dx.doi.org/10.1007/s13346-019-00617-2

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