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Deletion of the Ca(2+) Channel Subunit α(2)δ3 Differentially Affects Ca(v)2.1 and Ca(v)2.2 Currents in Cultured Spiral Ganglion Neurons Before and After the Onset of Hearing

Voltage-gated Ca(2+) channels are composed of a pore-forming α(1) subunit and auxiliary β and α(2)δ subunits, which modulate Ca(2+) current properties and channel trafficking. So far, the partial redundancy and specificity of α(1) for α(2)δ subunits in the CNS have remained largely elusive. Mature s...

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Detalles Bibliográficos
Autores principales: Stephani, Friederike, Scheuer, Veronika, Eckrich, Tobias, Blum, Kerstin, Wang, Wenying, Obermair, Gerald J., Engel, Jutta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606706/
https://www.ncbi.nlm.nih.gov/pubmed/31293392
http://dx.doi.org/10.3389/fncel.2019.00278