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Deletion of the Ca(2+) Channel Subunit α(2)δ3 Differentially Affects Ca(v)2.1 and Ca(v)2.2 Currents in Cultured Spiral Ganglion Neurons Before and After the Onset of Hearing
Voltage-gated Ca(2+) channels are composed of a pore-forming α(1) subunit and auxiliary β and α(2)δ subunits, which modulate Ca(2+) current properties and channel trafficking. So far, the partial redundancy and specificity of α(1) for α(2)δ subunits in the CNS have remained largely elusive. Mature s...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606706/ https://www.ncbi.nlm.nih.gov/pubmed/31293392 http://dx.doi.org/10.3389/fncel.2019.00278 |