Deletion of the Ca(2+) Channel Subunit α(2)δ3 Differentially Affects Ca(v)2.1 and Ca(v)2.2 Currents in Cultured Spiral Ganglion Neurons Before and After the Onset of Hearing

Voltage-gated Ca(2+) channels are composed of a pore-forming α(1) subunit and auxiliary β and α(2)δ subunits, which modulate Ca(2+) current properties and channel trafficking. So far, the partial redundancy and specificity of α(1) for α(2)δ subunits in the CNS have remained largely elusive. Mature s...

Descripción completa

Detalles Bibliográficos
Autores principales: Stephani, Friederike, Scheuer, Veronika, Eckrich, Tobias, Blum, Kerstin, Wang, Wenying, Obermair, Gerald J., Engel, Jutta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606706/
https://www.ncbi.nlm.nih.gov/pubmed/31293392
http://dx.doi.org/10.3389/fncel.2019.00278

Ejemplares similares

Ejemplares similares