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Fine-Tuning of Type I Interferon Response by STAT3

Type I interferon (IFN-I) is induced during innate immune response and is required for initiating antiviral activity, growth inhibition, and immunomodulation. STAT1, STAT2, and STAT3 are activated in response to IFN-I stimulation. STAT1, STAT2, and IRF9 form ISGF3 complex which transactivates downst...

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Detalles Bibliográficos
Autores principales: Tsai, Ming-Hsun, Pai, Li-Mei, Lee, Chien-Kuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606715/
https://www.ncbi.nlm.nih.gov/pubmed/31293595
http://dx.doi.org/10.3389/fimmu.2019.01448