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Tau Secretion: Good and Bad for Neurons

In Alzheimer’s disease (AD), neurofibrillary tangles (NFTs), lesions composed of hyperphosphorylated and aggregated tau, spread from the transentorhinal cortex to the hippocampal formation and neocortex. Growing evidence indicates that tau pathology propagates trans-synaptically, implying that patho...

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Detalles Bibliográficos
Autores principales: Pernègre, Camille, Duquette, Antoine, Leclerc, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606725/
https://www.ncbi.nlm.nih.gov/pubmed/31293374
http://dx.doi.org/10.3389/fnins.2019.00649