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Manganese-Induced Neurotoxicity: New Insights Into the Triad of Protein Misfolding, Mitochondrial Impairment, and Neuroinflammation

Occupational or environmental exposure to manganese (Mn) can lead to the development of “Manganism,” a neurological condition showing certain motor symptoms similar to Parkinson’s disease (PD). Like PD, Mn toxicity is seen in the central nervous system mainly affecting nigrostriatal neuronal circuit...

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Detalles Bibliográficos
Autores principales: Harischandra, Dilshan S., Ghaisas, Shivani, Zenitsky, Gary, Jin, Huajun, Kanthasamy, Arthi, Anantharam, Vellareddy, Kanthasamy, Anumantha G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606738/
https://www.ncbi.nlm.nih.gov/pubmed/31293375
http://dx.doi.org/10.3389/fnins.2019.00654