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Stargazin and γ4 slow the channel opening and closing rates of GluA4 AMPA receptors

As auxiliary subunits, transmembrane AMPA receptor regulatory proteins (TARPs) are known to enhance macroscopic current amplitude and alter kinetic properties of AMPA receptors on slow time scale, such as desensitization rate. Whether TARPs affect the rate of AMPA channel opening and closing, howeve...

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Detalles Bibliográficos
Autores principales: Pierce, Vincen D., Niu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606765/
https://www.ncbi.nlm.nih.gov/pubmed/31267004
http://dx.doi.org/10.1038/s41598-019-45870-0